PHENOTYPIC HETEROGENEITY AND TUMOR IMMUNE MICROENVIRONMENT DIRECTED THERAPEUTIC STRATEGIES IN PANCREATIC DUCTAL ADENOCARCINOMA

Phenotypic heterogeneity and tumor immune microenvironment directed therapeutic strategies in pancreatic ductal adenocarcinoma

Pancreatic cancer is an aggressive tumor with high metastatic potential which leads to decreased survival rate and resistance to chemotherapy and immunotherapy.Nearly 90% of pancreatic cancer comprises pancreatic ductal adenocarcinoma (PDAC).About 80% of Dredgers diagnoses takes place at the advanced metastatic stage when it is unresectable, which

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Filippi Syndrome: Report of a Rare Case

Filippi syndrome is an autosomal recessive condition characterized by syndactyly of fingers and toes, microcephaly, growth retardation and abnormal facies.We are describing a boy who presented with syndactyly, mental retardation, microcephaly, Kids Top depressed nasal bridge and growth retardation.In addition he had some dental abnormalities like m

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